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Bosentan Therapy for Pulmonary Arterial Hypertension - Actelion's slide show presentation to the FDA.
www.fda.gov/ohrms/dockets/ac/01/slides/3775S2_01_ACTELION/Index.htm
FDA Approves First Oral Medication for Pulmonary Arterial Hypertension - Describes the trial results and subsequent approval of Tracleer.
www.fda.gov/bbs/topics/ANSWERS/2001/ANS01121.html
Pharmacodynamics and Drug Action - PDF report of an investigation into potential liver damage from bosentan use. [Acrobat Reader required]
www.ikp.unibe.ch/lab2/CPT.pdf
Tracleer - Features an overview of pulmonary hypertension, prescribing information for US residents, and press releases.
www.tracleer.com